University of California, Davis researchers have created a non-hallucinogenic version of ibogaine. The new substance could prove just as effective as the psychedelic original used to treat addiction and psychological illnesses such as depression and post-traumatic stress disorder.
David Olson, an assistant professor of chemistry at UC Davis, detailed the discovery in the December 2020 issue of Nature.
In the study, a series of rodent experiments showed that mice decreased their alcohol consumption and experienced a delayed opiate relapse when given the non-hallucinogenic Tabernanthalog (TBG). The synthetic version is water-soluble and has fewer adverse effects than ibogaine. Olson says he’s optimistic that TBG can treat addiction and many illnesses related to addiction, such as depression and anxiety.
Read the full article here: https://www.ucdavis.edu/news/new-compound-related-psychedelic-ibogaine-could-treat-addiction-depression