Psychedelic Drug Attracts Corporate Attention

n the United States, over 2 million Americans suffered from opioid addiction in 2018. With relapse rates of traditional rehabilitative models averaging at about 50%, companies have positioned themselves within the psychedelic drug sector to bring a different therapeutic approach.

Companies such as ATAI Sciences and DemeRx are investigating ibogaine, a natural extract found in western Central Africa that has proven effective in reducing opioid withdrawal symptoms and cravings. Researchers also found that the same substance lessens depression that accompanies addiction. Despite the positive effects, ibogaine continues to be classified as a Schedule 1 drug not allowed for medical use in the United States. Regardless of the status, researchers continue to study precisely how ibogaine affects the brain and delivers relief to those suffering from addiction. It is believed that ibogaine affects neurotransmitter systems, including serotonin, NMDA, and opioid receptors.

Read the full article here: https://www.epmmagazine.com/pharmaceutical-industry-insights/how-psychedelic-medicine-is-being-used-in-the-fight-to-end-o/

Ibogaine Attracts Addiction Research

Researchers continue to examine the therapeutic properties of ibogaine as it proves effective in addiction rehabilitation. Countries such as New Zealand, Brazil, and South Africa allow it for medical use. In the United States, ibogaine is a Schedule 1 substance, which means it is not approved for medical use. 

Ibogaine is an indole alkaloid produced by the Taberna iboga shrub native to West Africa. Traditionally, consumers used the substance to reduce fever, boost sexual arousal, and improve health. Specifically, it has been found to bring on a psychedelic experience in larger doses, while decreasing opioid withdrawal symptoms and disrupting cravings. Researchers have also shown it to be effective in combatting depression and alcohol abuse. Like with all drugs, care must be exercised when using ibogaine. It has been found to potentially cause paralysis, heart or pulmonary failure, and seizures in rare cases.

Read the full article here: https://www.medicalnewstoday.com/articles/ibogaine-for-addicition

The Promise of Ibogaine

Traditional rehabilitative models are failing to deliver results to those trying to beat chronic drug abuse. Some are hailing the increasing popular extract ibogaine for its suppressive effects on withdrawal symptoms and ultimately, addiction.

Ibogaine, derived from a central west African shrub, is a psychedelic drug that has proven effective in treating alcohol, heroin, and opioid addiction in treatment centers worldwide. Scientists continue to study ibogaine to unlock its therapeutic power. One theory researchers have for ibogaine’s effectiveness is that it may increase brain neuron growth and plasticity, which is the brain’s ability to remodel itself. While human clinical trials are underway and pharmaceutical companies and government agencies worldwide continue to investigate ibogaine’s seemingly anti-addiction properties, some U.S. military veterans have found relief using the psychedelic drug. 

Read the full article here: https://time.com/5951772/ibogaine-drug-treatment-addiction/

Ibogaine PHARMACOLOGY

Heroin and cocaine addiction is not only physically and psychologically harmful to the addict; the impact on family members, friends, and employment is equally destructive. Ibogaine, an indole alkaloid from the West African shrub, Tabernanthe iboga, has proven effective in treating a wide range of addictions. It is part of a larger alternative drug rehabilitation movement, and a fascinating study calling on 191 volunteers details its effectiveness. 

Researchers concluded in “Ibogaine Detoxification Transitions Opioid and Cocaine Abusers Between Dependence and Abstinence: Clinical Observations and Treatment Outcomes” that ibogaine therapy administered under treatment professionals in safe doses diminishes the withdrawal symptoms from opioids and reduces drug cravings. This is excellent news not only for heroin rehabilitation but also for fentanyl detox, among others. Ibogaine treatment in Mexico has been developing rapidly and the study’s authors conclude that product development of single dose ibogaine holds great promise moving forward. 

Read the full article here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996271/